Experiencing the same problem? Setting up a connection to a published app or desktop takes a while? (20 to 60 sec) You might have Citrix Session Reliability configured but the (Windows) Firewall blocks port 2598/TCP resulting in a session over port 1494/TCP. It will take a while before the detection occurs, that’s what is causing the delay.
Resolution, in my order of preferences:
1) Open up port 2598/TCP (to enable Session Reliability for XenApp or XenDesktop VDI)
2) Disable Citrix Session Reliability by GPO (So it is not going to try to setup the connection)